Clonazepam

Indications & formulation #

Panic disorder in adults; seizure treatment has a separate schedule. This reference covers the selected formulation; other indications and products need their own evidence.

Dose reference #

Adult educational reference · Oral tablet · United States. The clinician selects treatment after assessment; this page does not calculate or change a prescription.

Start 0.25 mg twice daily; the usual target is 1 mg/day after three days. Some patients require more; selected panic maximum 4 mg/day.

Contraindications & important cautions #

Avoid significant hepatic disease and acute narrow-angle glaucoma. Opioids/alcohol increase respiratory depression; dependence and withdrawal can be severe.

Selected important cautions; consult the full product information for all contraindications and warnings.

Adverse effects #

Sedation, ataxia, cognitive effects, dependence and withdrawal.

Interactions #

Alcohol, opioids and other sedatives increase respiratory risk.

Monitoring #

Review sedation, functioning, respiratory vulnerability, duration and taper planning.

Special populations #

Use cautious lower dosing in older adults; review respiratory disease, renal illness and pregnancy/neonatal sedation risk.

Adult scope. Pregnancy, breastfeeding and pediatric use require the exact product’s population-specific guidance and individual assessment.

Discontinuation, restarting & counseling #

Use an individualized gradual taper. Abrupt cessation can cause withdrawal seizures.

Brands & products #

Reference coverage #

Structured summary of selected adult uses, not an exhaustive monograph. Indian product authorization and local prescribing requirements have not been reconciled.